The diagnosis of fibromyalgia is a fairly new one. The group of symptoms collectively classified as fibromyalgia has been recognized as a separate diagnosis only recently. As a result, there are few drugs that have been studied and approved by the FDA for the treatment of the condition. To date, there are only two medications approved for the treatment of fibromyalgia; pregabalin (Lyrica®) and duloxetine (Cymbalta®).
Lyrica® was the first drug approved for the treatment of fibromyalgia. It has anti-seizure, anti-anxiety and pain relief properties. It is often used to treat nerve pain. Because of its pain relief properties, it may work well for the symptoms of fibromyalgia. Further, the anti-anxiety properties of the medication may help promote an overall feeling of well being. Lyrica® can be sedating so it may help promote sleep, however, one must take care when operating machinery or driving a car while taking the medication.
Cymbalta® is the newest drug approved for the treatment of fibromyalgia. Approved in June 2008, it was first used to treat anxiety, depression and nerve pain. Cymbalta® is thought to act on two brain chemicals; serotonin and norepinephrine. It is thought that these two chemicals may play a role in certain types of pain. Its anti-depression properties may also help promote sleep and mood.
Although these medications may help with symptoms, the benefits of using such medication should be weighed against the risks. Constipation, weight gain, headache, confusion, dizziness, sexual dysfunction and suicidal ideation are all potential side effects for these medications. Talk things over with your doctor carefully before beginning one of these drugs for your condition. Have your doctor discuss non-medical therapies such as exercise, behavioral therapy and education too as they have been proven to help with symptoms as well.(1) It may take some trial and error, but together you and your physician can find which therapies will work right for you.
Author: Christi Larson, Pharm. D.
Dr. Larson is a Clinical Infusion Pharmacist, author of Empowered Medicine; A Guide for Consumers and creator of www.empoweredmedicine.com. You can read more about her by visiting www.EmpoweredMedicine.com and clicking on the 'About Us' tab. EmpoweredMedicine.com is committed to providing evidence-based medical information.
