It is felt that the new recommendation may help decrease the incidence of liver toxicity for those that may be more sensitive to liver problems. For some, taking 6000mg for just two days has caused liver toxicity. People whose livers may already be compromised due to hepatitis or alcohol intake may be especially at risk. Finally, some do not realize that there are many products out there that have acetaminophen in them in combination with other ingredients. Therefore, they may not realize they are exceeding the maximum daily dose of acetaminophen.

It is important to read labels carefully when taking any over-the-counter medication to see if it contains acetaminophen. Also, note that most studies have shown two 325mg tablets to be as effective as taking two 500mg tablets for pain. Products that contain acetaminophen may list the ingredient as ‘APAP’. If you are unsure if a certain product contains acetaminophen or not, ask your pharmacist.